Kirkman’s Maximum Spectrum Enzym-Complete/DPP-IV™ Fruit Free w/Isogest® capsules are free of fruit derived enzymes, such as bromelain, kiwi and papaya that can occasionally cause issues for some sensitive individuals.
This product differs from Kirkman’s EnZym-Complete/DPP-IV™ II with Isogest® by including additional disaccharidase enzyme activity to more completely breakdown complex disaccharides and carbohydrates, such as sugars and starches, to the monosaccharides glucose and fructose.
However, like EnZym-Complete/DPP-IV™ II with Isogest®, it is a comprehensive multiple enzyme formulation that acts on all food groups. In addition to the carbohydrase enzymes, it contains proteases, peptidases, lipase, cellulase, phytase and amylases for complete digestive support.
Disaccharidase enzymes in the product with increased concentrations include: lactase for additional lactose digestion; maltase for additional maltose digestion; glucoamylase for polysaccharide and starch digestion; and Isogest®, Kirkman’s exclusive specialty enzyme for addressing isomaltase insufficiency. Kirkman® products are the only commercially available enzyme products that contain this isomaltase activity.
The importance of this missing enzyme fraction was confirmed in January 2004 by R. Kushak, PhD and T. Buie, MD of Massachusetts General Children’s Hospital in an intestinal biopsy study involving 100 children with special requirements and sensitivities. The study showed that 60% of these patients had weak lactase activity and 25-45% had weak isomaltase/palatinase activity, which substantiated their special dietary need for an enzyme providing isomaltase/palatinase activity.
This study provided the impetus for Kirkman® to search for an enzyme that had isomaltase/palatinase activity. Kirkman® found that enzyme and trademarked it Isogest®.
Isogest® has the ability to split isomaltose into two molecules of glucose and to split palatinose into one molecule of glucose and one molecule of fructose. The result of including this new enzyme is better, more complete carbohydrate digestion. Currently, no other enzyme product can offer this added activity.
The presence of Isogest® gives this product the equivalent activity of the isomaltase fraction of the sucrase/isomaltase enzyme found in the human digestive system.
Physicians and parents who evaluated products containing Kirkman’s Isogest® reported the following:
• less bloating
• more regular bowel habits
• less constipation
• more normal stools
• better overall digestion with less discomfort
• firmer stools
• less gas
• less diarrhea
• less sensitivity to dairy and grains
• less odorous bowel movements
No adverse effects were reported.